Summarized by Masters of Longevity from Longevity Technology.
A short article previewing clinical Phase 1b results on a topical treatment's effects on skin epigenetic age and related molecular markers, inviting readers curious about translational longevity research.
Key Takeaways
- Topical RLS-1496 treatment produced a mean reduction of 2.1 years in skin epigenetic age across 11 paired photoaged samples.
- One participant showed an 11.7-year reduction in skin epigenetic age at Day 63 following treatment.
- Molecular assays reported DNA methylation shifts counter to aging patterns, a 10% rise in type III collagen, and reduced circulating CCL22.
