News summary

Pelacarsen cut Lp(a) 78% but not cardiovascular events in HORIZON

Source: Longevity Docs News • Published: 09 Nov 2026, 00:00

Summarized by Masters of Longevity from Longevity Docs News.

In 8,322 patients over 4.7 years, pelacarsen sharply lowered Lp(a) but not events.

Pelacarsen cut Lp(a) 78% but not cardiovascular events in HORIZON
Key Takeaways
  • Pelacarsen lowered Lp(a) by about 75% for nearly five years.
  • Event rates were 12.3% with drug and 12.1% with placebo.
  • This randomized secondary‑prevention trial was funded by Novartis.
Read the full article at Longevity Docs News ↗

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