Summarized by Masters of Longevity from Nature - Biotechnology.
Reports a mechanism where nutrient stress upregulates ACSS1 in bone marrow skeletal stem cells, impairing mitochondrial function and osteogenesis and linking metabolic excess to bone loss.
Key Takeaways
- View all journals Nutrient stress-driven ACSS1 controls metabolic flexibility and bone formation We’re sharing this article early to provide faster access to peer-reviewed, accepted research.
- Although acetate metabolism is linked to diabetes and alcoholism, its role in the skeletal complications of these conditions remains unknown.
