Summarized by Masters of Longevity from Aging Cell.
Motor-cortex excitability and its relationship to declining neuromuscular performance in aged mice — a concise preview of the study’s focus and reader payoff.
Key Takeaways
- Aged mice showed increased motor cortex hyperexcitability measured by in vivo electrophysiology compared with young controls.
- Hyperexcitability correlated with reduced neuromuscular performance on behavioral motor tests in the same animals.
- Findings suggest cortical functional changes accompany peripheral neuromuscular decline during aging in mice.
