Summarized by Masters of Longevity from Longevity Docs News.
Menopausal care guidance: what clinicians need from an updated practice guideline on treating hot flushes, sleep, and mood symptoms.

Key Takeaways
- ACOG strongly recommends systemic menopausal hormone therapy for vasomotor symptoms and related sleep disturbance in patients without contraindications when started before age 60 or within ten years of natural menopause.
- Randomized trials show hormone therapy reduces hot flush frequency by about 57% and severity by about 71%, with transdermal estradiol plus progestogen ranked most effective.
- For patients who cannot or will not take hormones, SSRIs/SNRIs and neurokinin receptor antagonists are strongly recommended, while behavioral therapies and gabapentin are considered conditional options.



