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MCP‐1 From Aging Dermal Adipose Tissue Impairs Hair Follicle Cycling via Macrophage Recruitment: Implications for Age‐Related Alopecia

Source: Aging Cell • Published: 09 Nov 2026, 03:39

Summarized by Masters of Longevity from Aging Cell.

Aging dermal adipose tissue increases MCP-1 and recruits macrophages, impairing hair cycling.

MCP‐1 From Aging Dermal Adipose Tissue Impairs Hair Follicle Cycling via Macrophage Recruitment: Implications for Age‐Related Alopecia
Key Takeaways
  • Aging dermal adipose tissue is reported to express higher MCP-1.
  • Elevated MCP-1 was found to recruit macrophages to hair follicles.
  • Modulating MCP-1 or macrophage recruitment rescued cycle defects in models.
Read the full article at Aging Cell ↗

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