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Late Life Asparagine Endopeptidase Inhibition Extends Lifespan in Mice

Source: Fight Aging! • Published: 11 Nov 2026, 19:22

Summarized by Masters of Longevity from Fight Aging!.

Pharmacological AEP inhibition started at 18 months increased median survival by four months.

Late Life Asparagine Endopeptidase Inhibition Extends Lifespan in Mice
Key Takeaways
  • AEP inhibition from 18 months increased median mouse lifespan.
  • #11a treatment improved physical and cognitive frailty measures.
  • #11a preserved NAMPT and raised NAD+-related signals.
Read the full article at Fight Aging! ↗

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