Summarized by Masters of Longevity from Longevity Docs News.
A national cohort study used wrist accelerometer data to link greater night-to-night sleep timing variability with higher subsequent mortality risk over about seven years.
Key Takeaways
- Each 1-hour increase in night-to-night standard deviation of sleep midpoint was associated with a 22% higher all-cause mortality hazard.
- Sleep onset variability showed a 19% higher all-cause mortality hazard while total sleep time variability showed a 17% higher hazard.
- A cell experiment found irregular synchronization reduced clock-gene expression and increased inflammatory and adhesion markers in endothelial cells.
