Summarized by Masters of Longevity from Fight Aging!.
Interactions between exercise and the gut microbiome are explored in a narrative review on their roles in muscle aging and frailty, inviting readers curious about mechanistic links.

Key Takeaways
- Age-related gut microbiome shifts associate with frailty and reduced physical function in older human cohorts.
- Exercise correlates with healthier microbiome composition, improved mitochondrial function, insulin sensitivity, and reduced inflammation.
- Fecal microbiota transplantation from young to old animals improved healthspan and lifespan in preclinical studies.



