Summarized by Masters of Longevity from Frontiers - Health.
Risk-stratification article outlining how combining blood, echo, and CT measures could guide monitoring and prevention of chemo-related heart injury.
Key Takeaways
- Baseline hs-cTnI, GLS, and CAC were evaluated together to predict chemotherapy-related cardiac dysfunction in multiple myeloma patients.
- A multi-domain risk score labeled MY-CARD was developed and internally validated using a derivation cohort of 248 and validation cohort of 64 patients.
- GLS was prioritized over LVEF in predictive models because it detects subclinical systolic dysfunction before overt LVEF decline.
