Summarized by Masters of Longevity from Aging Cell.
Aged male mouse muscle had reduced exercise‑induced mitophagy and altered mitoAMPKα.
Key Takeaways
- Aged male mice showed blunted mitophagy after exercise stimulus.
- Mitochondrial AMPKα localization and phosphorylation were changed with age.
- Altered mitoAMPKα coincided with impaired mitophagy, not preceding it.
