News summary

FGF13 Alleviates the Aging Process in Mice by Regulating Astrocyte Function in the Medial Prefrontal Cortex via Phafin2 Signaling Pathway

Source: Aging Cell • Published: 26 Oct 2026, 03:47

Summarized by Masters of Longevity from Aging Cell.

In mice, FGF13 modified medial prefrontal cortex astrocytes and reduced aging features.

FGF13 Alleviates the Aging Process in Mice by Regulating Astrocyte Function in the Medial Prefrontal Cortex via Phafin2 Signaling Pathway
Key Takeaways
  • FGF13 improved astrocyte structure and markers in aged mice.
  • FGF13 lessened aging-related cellular and behavioral changes via Phafin2.
  • Evidence is from mice and causal effects in humans remain unproven.
Read the full article at Aging Cell ↗

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