News summary

Feedforward–feedback mismatch as a biocybernetic hypothesis for postprandial glycemic dysregulation in type 2 diabetes mellitus

Source: Frontiers - Health • Published: 09 Nov 2026, 00:00

Summarized by Masters of Longevity from Frontiers - Health.

Authors propose sensory desensitization and delayed control worsen post-meal glucose.

Feedforward–feedback mismatch as a biocybernetic hypothesis for postprandial glycemic dysregulation in type 2 diabetes mellitus
Key Takeaways
  • Weakened feedforward sensing was proposed to worsen postprandial glycemia.
  • Reduced oral-cephalic signaling can delay regulatory responses and overshoot.
  • Metabolic re-sensitization has not established clinical efficacy yet.
Read the full article at Frontiers - Health ↗

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