Summarized by Masters of Longevity from Longevity Docs News.
This article previews a lab and animal study showing how exercise-altered blood vesicles might reactivate a youthful cartilage gene, suggesting a possible molecular link between aerobic activity and joint rejuvenation.
Key Takeaways
- Three months of aerobic exercise raised miR-29 levels in extracellular vesicles isolated from older adults' blood.
- Injecting exercise-primed human vesicles into aged mouse knees restored Klotho expression and improved cartilage health.
- Engineered vesicles delivering miR-29 replicated cartilage benefits through a Klotho-dependent pathway in mice.
