Summarized by Masters of Longevity from Neuroscience News.
A meta-analysis found enriched housing consistently upregulates synaptic genes via AP-1.

Key Takeaways
- Meta-analysis showed conserved synaptic gene upregulation in rodents.
- AP-1 was identified as a central transcriptional driver of plasticity.
- Rodent findings have not established direct applicability to humans.



