Summarized by Masters of Longevity from Nature Aging.
Research brief describing a peer-reviewed article on how a specific immune-cell subset influences age-related shifts in blood-cell production, inviting readers to learn about the experimental approach and implications for rejuvenating immune balance.
Key Takeaways
- View all journals Aging is associated with myeloid-biased hematopoiesis, which leads to the establishment of a pro-inflammatory microenvironment.
- We discovered that cytotoxic CD4 + T cells foster this process via the CCL5–CCR5 axis and found that the clinically approved CCR5 antagonist maraviroc can rebalance immunity in aged mice.
