News summary

CSL and Alentis announce global partnership to develop and commercialise lixudebart for rare kidney and liver diseases

Source: PR Newswire • Published: 04 Oct 2026, 21:42

Summarized by Masters of Longevity from PR Newswire.

Announcement of an exclusive global collaboration to co-develop and commercialise a claudin-1 targeting monoclonal antibody for rare kidney and liver diseases, including AAV-RPGN, FSGS, and PSC.

CSL and Alentis announce global partnership to develop and commercialise lixudebart for rare kidney and liver diseases
Key Takeaways
  • CSL will pay Alentis an upfront US$355 million and Alentis can receive up to US$1.2 billion in commercial milestones.
  • CSL will fully fund completion of the ongoing Phase 2 RENAL trial and planned Phase 3 trial plus Phase 2 studies in FSGS and PSC.
  • If commercialised, global profits will be shared 55% to CSL and 45% to Alentis.
Read the full article at PR Newswire ↗

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