Summarized by Masters of Longevity from Nature - Main.
Reports a large genetics and population study proposing a 'circadian depression' subtype marked by disrupted sleep, low daytime activity, and distinct clinical features.
Key Takeaways
- A study of 11,380 people with severe depression classified about 2,604 individuals as having circadian depression using at least three of six criteria.
- Circadian depression cases showed higher genetic risk scores linked to ADHD, anxiety, and major depressive disorder.
- Circadian depression was associated with increased markers of inflammation and signs of disrupted metabolism.
