Summarized by Masters of Longevity from Neuroscience News.
Gladstone mapped 92 plasma proteins crossing the intact blood–brain barrier.
Key Takeaways
- Researchers mapped 92 proteins transported into mouse brains.
- In Alzheimer models, transport of APOA1 and others failed early.
- Restoring systemic APOA1 rescued neuronal connectivity in preclinical models.
