News summary

Association between estimated glucose disposal rate and subclinical cerebrovascular atherosclerotic burden in non-diabetic middle-aged and older adults

Source: Frontiers - Health • Published: 20 Oct 2026, 00:00

Summarized by Masters of Longevity from Frontiers - Health.

Estimated glucose disposal rate is used to examine links between insulin resistance and overall subclinical cerebrovascular atherosclerotic burden; a community-imaging study inviting readers to review methods and implications.

Association between estimated glucose disposal rate and subclinical cerebrovascular atherosclerotic burden in non-diabetic middle-aged and older adults
Key Takeaways
  • Lower eGDR, a surrogate marker of insulin resistance, was associated with higher subclinical cerebrovascular atherosclerotic burden.
  • Study analyzed community-dwelling adults aged 45 and older without diagnosed diabetes using multimodal cerebrovascular imaging.
  • The analysis adjusted for clinical and laboratory covariates and assessed dose-response relationships between eGDR and atherosclerotic burden.
Read the full article at Frontiers - Health ↗

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