News summary

Arrowhead’s shot under the skin cut spinal fluid tau by 73%

Source: Longevity Technology • Published: 26 Oct 2026, 16:38

Summarized by Masters of Longevity from Longevity Technology.

ARO‑MAPT lowered CSF tau by about 73% after a subcutaneous dose in healthy adults.

Arrowhead’s shot under the skin cut spinal fluid tau by 73%
Key Takeaways
  • A subcutaneous RNAi drug reduced CSF tau by about 73% in volunteers.
  • The treatment was generally well tolerated with mostly mild adverse events.
  • Effects on brain tangles and cognition remain unproven in patients.
Read the full article at Longevity Technology ↗

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