Summarized by Masters of Longevity from PR Newswire.
Two oral small molecules showed promising PK and reduced weight in animal models.
Key Takeaways
- AMB-895 showed sustained target coverage above EC70 for one week in primates.
- Once-weekly AMB-895 dosing reduced food intake and caused about 8% weight loss.
- AMB-131 increased 24-hour exposure and enhanced semaglutide weight loss in mice.
