Summarized by Masters of Longevity from Frontiers - Health.
Muscle-specific Keap1 deletion reduced infarct size and improved post-I/R cardiac function.
Key Takeaways
- Keap1 deletion increased Nrf2 protein in skeletal muscle only.
- Keap1 knockout mice showed smaller infarcts and better recovery.
- NQO1 and SOD2 were increased in muscle, plasma, and myocardium.
