Summarized by Masters of Longevity from Fight Aging!.
Gut microbiome changes across age groups: a systematic review article summarizing human studies that compare microbial composition and functional patterns between younger, older, and long-lived adults, offering insights useful for readers interested in how gut ecology relates to healthy ageing.
Key Takeaways
- The review included 41 human studies using mostly 16S rRNA sequencing and shotgun metagenomics.
- Centenarians showed consistent enrichment of Akkermansia, Alistipes, and Parabacteroides compared with younger groups.
- Age-related functional shifts involved amino acid catabolism, vitamin biosynthesis, and pathways linked to inflammation and gut barrier support.
