Summarized by Masters of Longevity from Lifespan.io.
Researchers found HDAC7 promotes tau phosphorylation and cognitive deficits in mouse models.
Key Takeaways
- HDAC7 is increased in mice and human Alzheimer’s brain tissue.
- HDAC7 was found to bind GSK3β and tau forming a complex.
- Deleting HDAC7 was found to reduce tau phosphorylation and improve cognition.
