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A multinational pharmacoepidemiology atlas of prescription medication associations with all-cause mortality across six population cohorts

Source: medRxiv • Published: 13 Nov 2026, 00:00

Summarized by Masters of Longevity from medRxiv.

Screening 8.93 million adults found most drugs linked to higher mortality, but a few showed inverse associations.

A multinational pharmacoepidemiology atlas of prescription medication associations with all-cause mortality across six population cohorts
Key Takeaways
  • Most medications were associated with higher mortality due to confounding.
  • VZV vaccine association with lower mortality was found across cohorts.
  • Randomized trials have not established that VZV reduces mortality.
Read the full article at medRxiv ↗

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