News summary

A commercial C3c ELISA as a diagnostic tool for complete complement factor I deficiency

Source: Frontiers - Health • Published: 29 Oct 2026, 00:00

Summarized by Masters of Longevity from Frontiers - Health.

A commercial C3c ELISA found undetectable C3c in all FI-deficient patients.

A commercial C3c ELISA as a diagnostic tool for complete complement factor I deficiency
Key Takeaways
  • Plasma C3c was undetectable in all six FI-deficient patients.
  • Serum C3c testing reproduced separation across FI variant classes.
  • C3d and iC3b were unreliable, likely showing cross-reactivity.
Read the full article at Frontiers - Health ↗

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