Surface Transmon Resonance (STR): a handheld nanogap biosensor for real-time, label-free molecular binding kinetics
Researchers introduce Surface Transmon Resonance (STR), a nanogap electronic biosensor that uses a handheld nanoVNA for real-time, label-free detection of molecular binding kinetics at radio frequencies. Proof-of-concept BSA/anti-BSA measurements demonstrate SPR-like affinity and kinetic readouts in physiologic solutions, positioning STR as a low-cost, portable alternative for point-of-care molecular diagnostics.
Why it mattersSTR using a handheld nanoVNA enables SPR-like kinetics measurement, prompting prioritization of STR integration into POC diagnostic development.