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Scientists discover brain switches that clear Alzheimer’s plaques

Source: Science Daily - Health & Medicine | Published: 2026-02-20T23:17:17.651267+00:00

Scientists discover brain switches that clear Alzheimer’s plaques

Karolinska-linked study finds somatostatin receptor subtypes 1 and 4 upregulate neprilysin, lowering amyloid-beta and improving memory in mice, suggesting common drug targets could enable affordable oral Alzheimer's treatments.

Why it mattersPrioritize screening somatostatin receptor 1 and 4 agonists to advance oral Alzheimer's drug candidates.

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