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Resistance Exercise Training Slows Down Brain Aging

Source: Lifespan.io | Published: 2026-03-04T17:00:20+00:00

Resistance Exercise Training Slows Down Brain Aging

Randomized trial of 309 adults aged 62–70 compared one-year heavy resistance training, moderate-intensity resistance training, and a non-exercise control. Both exercise arms showed reduced brain age gaps measured by rs-fMRI brain-clock models trained on an independent 2,433-participant dataset; heavy resistance produced greater functional connectivity increases in prefrontal, motor, and superior parietal regions. Reported BAG reductions were roughly 1.4–1.84 years for heavy resistance and 1.39–2.26 years for moderate training at one year and one year post-intervention, and BAG changes correlated with gains in leg strength.

Why it mattersRs-fMRI brain clock detected 1.4–2.26-year BAG reductions after one-year resistance training.

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Anna Drangowska-Way

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