Multimodal sensing technologies for HPAI biosurveillance in poultry production systems
Nature Biotechnology review analyzes HPAI H5N1 clade 2.3.4.4b outbreaks that caused over 168 million bird depopulations and more than $1.4 billion in losses, and documents zoonotic spillover into dairy herds and human cases. It evaluates diagnostic bottlenecks and proposes integrating molecular amplification, electrochemical detection, acoustic anomaly analysis, and behavioral/physiological signals for decentralized, in situ One Health biosurveillance.
Why it mattersH5N1 spillover into dairy herds requires biosensor deployment to prioritize worker screening and farm quarantines.