Multifunctional hierarchical Ni2CoS4 structures for combating drug-resistant infections and colorectal cancer via piezocatalytic ROS generation
Hierarchical Ni2CoS4 (sample N3) was synthesized and activated by ultrasonication to generate reactive oxygen species. N3 rapidly degraded methylene blue, eradicated MDR bacterial biofilms, and induced dose-dependent cytotoxicity in HCT-116 colorectal cancer cells in vitro.
Why it matters99% biofilm eradication and MIC 5 µg/mL under ultrasonication show potent antimicrobial activity.