Higher tyrosine levels may trim years off life
A Mendelian randomization analysis of ~272,500 UK Biobank participants found genetically higher circulating tyrosine associated with shorter lifespan, with stronger effects observed in men. Authors link tyrosine to nutrient-sensing pathways and suggest specific amino acids — rather than overall protein or calories — could influence aging, while noting dataset overlap and limited power for sex-specific conclusions.
Why it mattersUK Biobank Mendelian randomization links higher tyrosine to shorter lifespan, stronger in men.
Entities Mentioned
UK BiobankAging
People Mentioned
Kyle Umipig