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Genetically modified pig liver keeps man alive until human organ transplant

Source: Nature - Biotechnology | Published: 2026-03-06T00:00:00+00:00

Genetically modified pig liver keeps man alive until human organ transplant

Surgeons at Xijing Hospital in Xi'an connected a genetically modified pig liver extracorporeally to a 56-year-old man with acute-on-chronic liver failure as a bridge to human transplantation; the ClonOrgan-supplied liver carried six genetic modifications, filtered the patient’s blood for several days without overt rejection, and the patient later received a human liver and is recovering.

Why it mattersXijing Hospital used a six-gene modified pig liver; monitoring immunosuppression dosing and liver-function data is needed for trial safety.

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