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First comparison of commercial systems to prepare nanofat: technical performances and biological quality differ among obtained products

Source: Nature - Biotechnology | Published: 2026-02-20T00:00:00+00:00

First comparison of commercial systems to prepare nanofat: technical performances and biological quality differ among obtained products

Head-to-head comparison of eight commercial nanofat preparation systems shows device-dependent differences in technical performance and biological quality; Adinizer delivered the highest adipose-derived stromal/stem cell yield, Puregraft Boost V2 and Emulsfat ranked best technically, Hy-Tissue Nanofat had low cell yields and high leukocyte proportions, and all devices preserved adipocytes, vascular networks, EVs, and clonogenic progenitors.

Why it mattersAdinizer yielded the highest adipose-derived stromal/stem cell counts, so clinicians should choose it when maximizing progenitor yield.

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