Discovery shines light on a cascade of events that occurs when toxic tau impacts synapses, suggesting new mechanisms for neurodegeneration
Buck Institute's Tracy lab reports in Molecular Neurodegeneration that toxic tau triggers a cascade at synapses, revealing a new mechanism driving synapse loss in Alzheimer's disease and related dementias.
Why it mattersBuck Institute's Tracy lab shows toxic tau drives synaptic cascade, prompting prioritization of tau-targeting synapse-protective therapeutics.