Beyond amyloid plaques: AI reveals hidden chemical changes across the Alzheimer’s brain
Researchers at Rice University created the first dye-free, full-brain molecular atlas of an Alzheimer’s brain using hyperspectral Raman imaging plus machine learning, revealing chemical alterations that extend beyond amyloid plaques and show major cholesterol and energy-metabolism shifts in key memory regions, suggesting whole-brain metabolic disruption rather than a solely protein-driven disease.
Why it mattersRice University used hyperspectral Raman imaging to show cholesterol and energy-molecule shifts in memory regions.
Entities Mentioned
Rice University