AI blood test finds silent liver disease years before symptoms
Johns Hopkins researchers developed an AI-driven liquid biopsy that analyzes genome-wide cell-free DNA fragmentation patterns to noninvasively detect early liver fibrosis and cirrhosis, identifying disease signals years before symptoms and potentially enabling earlier intervention to reduce cancer risk. The study appears in Science Translational Medicine.
Why it mattersJohns Hopkins used cell-free DNA fragmentomes to detect early liver fibrosis; prioritize diagnostic validation and clinical pathways.
Entities Mentioned
Science Translational Medicine