Aging is Often Overlooked in Mouse Models of Age-Related Conditions
Researchers warn that common Parkinson's disease mouse models often use toxin-based approaches in young animals, overlooking biological aging. The PD-AGE consortium, funded by the Michael J. Fox Foundation, produced a roadmap recommending prioritized aged models, standardized measurements, and harmonized protocols to improve translational relevance.
Why it mattersThe PD-AGE workshop produced a roadmap, prompting adoption of aged mouse models to improve PD drug translation.