Advanced alginate- nutriosomes for enhanced oral delivery of fermented Echium amoenum polyphenols
Alginate-nutriosome nanocarriers encapsulated fermented Echium amoenum polyphenols with >90% loading, 105–124 nm size, −56 mV zeta potential, PDI ≤0.19, stability in simulated saliva, gastric, and intestinal fluids, controlled release, and protective effects in stressed Caco-2 cells.
Why it mattersAlginate-nutriosomes showed >90% loading and stability in simulated GI fluids, indicating feasible oral delivery for nutraceutical development.