A hidden Aloe vera compound takes aim at Alzheimer’s
In silico screening of Aloe vera leaf compounds identified beta-sitosterol as a promising dual AChE and BChE inhibitor with stable binding and favorable safety indicators, positioning it as a candidate for experimental follow-up in Alzheimer’s drug development.
Why it mattersBeta-sitosterol's dual AChE/BChE inhibition suggests drug developers should prioritize in vitro validation and lead optimization.