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Troponin for surveillance of immune checkpoint inhibitor–associated myocarditis and post-therapy cardiovascular risk stratification: a systematic review and meta-analysis

Source: Frontiers - Health • Published: 26 Jun 2026, 00:00

Troponin for surveillance of immune checkpoint inhibitor–associated myocarditis and post-therapy cardiovascular risk stratification: a systematic review and meta-analysis

Assessment of troponin's role as a surveillance biomarker for immune checkpoint inhibitor cardiac toxicity and subsequent cardiovascular risk stratification.

Key Takeaways
  • Although the reported incidence of ICI-associated myocarditis is relatively low
  • Elevated troponin concentrations may reflect subclinical myocardial inflammation
  • All-cause mortality has not been systematically established
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