Read how an albumin-based nanoparticle curcumin formulation was tested for selective breast cancer killing and immune microenvironment remodeling in vitro.
Key Takeaways
- BC-NPs halved the IC50 in MCF-7 cells to 14.53 µM compared with free curcumin
- BC-NPs induced 44.0% apoptosis in MCF-7 cells versus 8.42% for free curcumin
- BC-NP treatment decreased TGF-β and IL-10 while increasing IFN-γ in co-culture